Protein Info for ABI39_RS11120 in Phocaeicola dorei CL03T12C01

Annotation: lipopolysaccharide biosynthesis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 478 transmembrane" amino acids 21 to 38 (18 residues), see Phobius details amino acids 44 to 63 (20 residues), see Phobius details amino acids 81 to 104 (24 residues), see Phobius details amino acids 116 to 137 (22 residues), see Phobius details amino acids 149 to 169 (21 residues), see Phobius details amino acids 175 to 192 (18 residues), see Phobius details amino acids 289 to 312 (24 residues), see Phobius details amino acids 326 to 346 (21 residues), see Phobius details amino acids 366 to 396 (31 residues), see Phobius details amino acids 416 to 437 (22 residues), see Phobius details amino acids 444 to 462 (19 residues), see Phobius details PF01943: Polysacc_synt" amino acids 10 to 276 (267 residues), 122.2 bits, see alignment E=4.3e-39 PF13440: Polysacc_synt_3" amino acids 33 to 322 (290 residues), 338.1 bits, see alignment E=6.8e-105 PF14667: Polysacc_synt_C" amino acids 326 to 463 (138 residues), 35.4 bits, see alignment E=1.8e-12

Best Hits

KEGG orthology group: None (inferred from 62% identity to osp:Odosp_2994)

MetaCyc: 40% identical to Escherichia coli O:113 antigen repeat unit flippase (Escherichia coli O113)
7.5.99.a [EC: 7.5.99.a]

Predicted SEED Role

"Lipopolysaccharide biosynthesis protein WzxC" in subsystem Colanic acid biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.99.a

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (478 amino acids)

>ABI39_RS11120 lipopolysaccharide biosynthesis protein (Phocaeicola dorei CL03T12C01)
MPDSLKQKAAKGVLWSTIERFSVQGVQFLIMIVMARLLTPHDYGIIGMLAIFIAVAQSLI
DSGFSQALIRKQNRTETDNNTVFYFNIVVSGLLYFILYISAPFVADFYNTPQLCPVMRVV
CISIIFNSLAVVQRALLTIKIDFKTQAKAALTAAVTSGVVGITMAYHGFGVWSLVTQQLL
NLGINTSLLWLLSKWRPRLIYSWQSFHELFAFGSKLLASGLLDTIYRNIYPIVIGKLFSA
SNLGHYTRAHQFSEFPSSNLTGIIQRVTYPVLCEIQNDDARLAGIYRKFLKLSAFIIFPL
MIGLSSVSRPFISIMLGQQWEFCGQLLQIICFSMMWYPIHAINLNLLQVKGRSDLFLRLE
IIKKILGVTVLCITAPFGLIVMCYGSILNSLVALVINTYYTGKLINVGFFKQMCDLLPTI
VLCLVMFVLILMVNYFIPSDIVKLCVGVAIGMTFYILSSHIFKFSELTEILSLLKRKP