Protein Info for ABI39_RS01160 in Phocaeicola dorei CL03T12C01

Annotation: alpha-L-fucosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01120: Alpha_L_fucos
  • amino acids 30 to 429 (400 residues), 292 bits, E=8.7e-91
• PF16757: Fucosidase_C
  • amino acids 467 to 546 (80 residues), 40 bits, E=4.9e-14

Best Hits

KEGG orthology group: K01206, alpha-L-fucosidase [EC: 3.2.1.51] (inferred from 98% identity to bvu:BVU_0217)

Predicted SEED Role

"Alpha-L-fucosidase (EC 3.2.1.51)" in subsystem L-fucose utilization or L-fucose utilization temp (EC 3.2.1.51)

MetaCyc Pathways

• xyloglucan degradation II (exoglucanase) (5/8 steps found)

KEGG Metabolic Maps

• Other glycan degradation

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.51

Use Curated BLAST to search for 3.2.1.51

Protein Sequence (548 amino acids)

>ABI39_RS01160 alpha-L-fucosidase (Phocaeicola dorei CL03T12C01)
MKAKHFLLASALLLWAGVLEAQTYQVPVSEKNEKMQEGEFEPTWESLQNYKVPEWFRNAK
FGIWAHWGPQCVEGSGDWMARSLYLEGSHEYKHHVEHYGHPSEVGFKDILPLFKAEKWDP
DKLVSFYKKIGAQYFFALGNHHDNYDLWDSQYQEWNSVNIGPKKDILAGWAEAAKKNGLP
FGISFHADHAWSWYEPAQRYDRHGEKAGVPYDGCLTKEDGKGKWWEGYDPQKLYAQNHPL
SAGSWADGMIHRQWVWGNGVCIPTQEYVTNFYDRTIDAINRYNPDLIYFDVTGVPFYPIS
DAGLKIAAHFYNHNMVARKGDFSAVMFGKILTDEQRKALVWDVERGSPNSIYEEPWQTCS
CLGGWHYDTRLAENGWYKSASDVVKLLVDVISKNGNLLLSVPLRADGTFDEKEEAILNEF
GDWMSMNKEAIYDTRPWKVFGEGPIANADIKINAQGFNEGAYTKATASEIRFTQTKKYLY
ATVLAWPEEKQVVIQSLATGSELYPDKITKIELLGYGKVFFTRTAQGVVIDMPDVQLNKI
APVFKIKK