Protein Info for ABI39_RS00370 in Phocaeicola dorei CL03T12C01

Annotation: DUF108 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 PF03447: NAD_binding_3" amino acids 8 to 125 (118 residues), 59.7 bits, see alignment E=7e-20 PF01958: Asp_DH_C" amino acids 170 to 247 (78 residues), 55.6 bits, see alignment E=7.6e-19

Best Hits

KEGG orthology group: K06989, aspartate dehydrogenase [EC: 1.4.1.21] (inferred from 98% identity to bvu:BVU_0071)

Predicted SEED Role

"L-Aspartate dehydrogenase (EC 1.4.1.21) homolog" (EC 1.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (262 amino acids)

>ABI39_RS00370 DUF108 domain-containing protein (Phocaeicola dorei CL03T12C01)
MNKLVIVGCGRLAEIITNAVVKGMLPDYELVGVYSRTASKAERIANKMRQHGKMCAACHT
LKELLELKPDYLVESASPAAMKELALPTLENGTSIITLSIGALADTSFYEKVKETAKAND
TRVYLVSGAIGGFDVLRTTSLMGNATARFFNEKGPDALKGTSVYKEELQQERCIVFSGNA
TEAINVFPTKVNVSVAASLASVGPDNMQVSIQSTPGFTGDTQKVEIKNEQVHAVVEVYSA
TSEIAGWSVVNTLLNITSPIVF