Protein Info for ABI39_RS00150 in Phocaeicola dorei CL03T12C01

Annotation: alpha-glucuronidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 681 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF07488: Glyco_hydro_67M" amino acids 129 to 403 (275 residues), 460.1 bits, see alignment E=4.1e-142 PF07477: Glyco_hydro_67C" amino acids 426 to 652 (227 residues), 313.6 bits, see alignment E=7.3e-98

Best Hits

KEGG orthology group: K01235, alpha-glucuronidase [EC: 3.2.1.139] (inferred from 92% identity to bvu:BVU_0029)

Predicted SEED Role

"Alpha-glucuronidase (EC 3.2.1.139)" in subsystem D-Galacturonate and D-Glucuronate Utilization (EC 3.2.1.139)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.139

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (681 amino acids)

>ABI39_RS00150 alpha-glucuronidase (Phocaeicola dorei CL03T12C01)
MKNMRLTVCIGIMCGWLAAGMLHAGTRPDHVRPVEEDGSRLWLPVIRPVEGAEVEITYKG
KVSPTIAIAIAELKNAWKGDPVLLEKKKTGRGDGFAITSSEHQVRILSSTETGLLYGAYS
LLRMQAAGQLTVPLSVTEQPAYDLRILNHWDNPDGTVERGYAGRSLWNWEELPGTLSPRY
EAYARANASVGINGTVLNNVNASPQVLTTGSLEKVKALADVFRPYGIKVYLSVNFASPIR
LGKLDTADPLDKEVIGWWKQKVKEIYAMIPDFGGFLVKANSEGQPGPCDFGRTHAEGANM
LADALKPYGGIVMWRAFVYSPTDSDRAKQAYLEFMPLDGQFRENVIVQIKNGPIDFQPRE
PYSPLFTAMKQTPMMVEFQITQEYLGFSNHLAYLAPLWEEFFGEVRPDRLKAAAGVANIG
MDANWCGHHFAQANWYAFGRLAWNPLLTSDRIADEWLQQTFTSQSAFVCPVKAMMLQSRE
AVVDYMMPLGLHHQFAWGHHYGPEPWCSVPGARPDWLPSYYHRADKEGIGFDRSSKGSNA
VSQYSDSLRLIYNDKTTCPEVYLLWFHHVPWQYRMKSGRTLWGELCRAYDRGVRQVRGFQ
EIWDSVEPFVDARRFREVQSKLKIQMRDAVWWKDACLLYFQTFSGMPIPAGIERPVHELE
DMKRFRLEISNYECPESGFNK