Protein Info for A4249_RS16130 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: ZIP family metal transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 43 to 63 (21 residues), see Phobius details amino acids 75 to 97 (23 residues), see Phobius details amino acids 118 to 140 (23 residues), see Phobius details amino acids 152 to 173 (22 residues), see Phobius details amino acids 180 to 202 (23 residues), see Phobius details amino acids 208 to 229 (22 residues), see Phobius details amino acids 241 to 259 (19 residues), see Phobius details PF02535: Zip" amino acids 117 to 255 (139 residues), 73.7 bits, see alignment E=8e-25

Best Hits

KEGG orthology group: K07238, zinc transporter, ZIP family (inferred from 55% identity to dsh:Dshi_3953)

Predicted SEED Role

"Metal transporter, ZIP family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I2W2 at UniProt or InterPro

Protein Sequence (260 amino acids)

>A4249_RS16130 ZIP family metal transporter (Brevundimonas sp. GW460-12-10-14-LB2)
MMESLSPIAAGGLGSLAAGMMTAVGAVPLLFFRKAGVQTQSALLGFAAGVMLAASFFSLI
IPGVDVLQAGGASPAAAAGVMGAAVLIGATVIGLMNRFAPVDMLAIGPAGSRDLSRRIWL
FIIAITLHNFPEGAAVGVSFGGGDLHQGLSTALGIGIQNMPEGLAVSAAMATLGYGRWPA
FAAALASGLVEPVGGLIGASVVDLLPGALPWGLGLAAGAMIYVVTAEIIPETREKSKGEG
SMIGLMIGLVGMMFLDIALG