Protein Info for A4249_RS13245 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: outer membrane beta-barrel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 385 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13505: OMP_b-brl" amino acids 9 to 241 (233 residues), 60.4 bits, see alignment E=6.3e-20 PF01389: OmpA_membrane" amino acids 26 to 244 (219 residues), 25.4 bits, see alignment E=2.8e-09 PF01617: Surface_Ag_2" amino acids 49 to 189 (141 residues), 22.1 bits, see alignment E=2.5e-08 PF02462: Opacity" amino acids 68 to 201 (134 residues), 22.7 bits, see alignment E=2.2e-08 PF00691: OmpA" amino acids 282 to 376 (95 residues), 62.8 bits, see alignment E=8.6e-21

Best Hits

Predicted SEED Role

"Outer membrane protein A precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HZI9 at UniProt or InterPro

Protein Sequence (385 amino acids)

>A4249_RS13245 outer membrane beta-barrel protein (Brevundimonas sp. GW460-12-10-14-LB2)
MKTFVLASSAAAALALSAGAVSAEPNGWYGAIDAGYHMIDDINAESSTTGANWNWEVNDG
WAAFARLGYRFNPNWRVELEGGYRSGDIGKVRAVTGTQGLCNLTPATGGCFSPEGDIESA
TLMANVIYDFGFEYWGVRPFVGLGAGVNRVDTNTIGALRANRLATFAADDTSTKFAAQAI
AGLAWAIGDRANIDLTYRYLTGDANFASTTAGTGVGATQFGEWDGDYDQSHTVTLGLRYS
FGAEDAPPPPPPPPPPPPPPPPPPPPPPPVAQTPVARQFVVYFDWDRSDLTAEARSVVTQ
AANYAKSGRPTRVLIVGYTDTSGSAAYNLGLSNRRSRTVADALVASGVNGGVIALDGKGE
TNLAKPTADGVREPLNRRATIDINF