Protein Info for A4249_RS11375 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: tRNA epoxyqueuosine(34) reductase QueG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 TIGR00276: epoxyqueuosine reductase" amino acids 9 to 341 (333 residues), 428.3 bits, see alignment E=9.7e-133 PF08331: QueG_DUF1730" amino acids 58 to 134 (77 residues), 83.7 bits, see alignment E=1.4e-27 PF13484: Fer4_16" amino acids 186 to 250 (65 residues), 78.3 bits, see alignment E=1.3e-25 PF13646: HEAT_2" amino acids 302 to 362 (61 residues), 30.6 bits, see alignment E=6.8e-11

Best Hits

Swiss-Prot: 58% identical to QUEG_ROSLO: Epoxyqueuosine reductase (queG) from Roseobacter litoralis (strain ATCC 49566 / DSM 6996 / JCM 21268 / NBRC 15278 / OCh 149)

KEGG orthology group: None (inferred from 76% identity to bsb:Bresu_3144)

Predicted SEED Role

"Iron-sulfur cluster-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I041 at UniProt or InterPro

Protein Sequence (369 amino acids)

>A4249_RS11375 tRNA epoxyqueuosine(34) reductase QueG (Brevundimonas sp. GW460-12-10-14-LB2)
MSDRLKTFIRQRAAELGFDVCRFASAADAWPAGERLRRFVDEGRHGAMEWMETTLDRRQH
PTAMWDEARTAIVLGMNYGPEQNPLDQLADRSAGYISVYARGDDYHEVIKGRLKQLAGQI
AARNGADIKVFVDTAPLMEKPLAQRAGLGWQGKHTNLLSRTHGNWLFLGTILTAAEIAPD
AAESEHCGRCTACLDACPTNAFPAPFQLDARRCLSYLTIEFAGPWPVEFRTLTGSRIYGC
DDCLAVCPWNKFAQEAREIRLLPREAFESPHLHDLLALDDAAFRALFTKSPVKRIGRDRF
LRNVLYAVGNSDDASLIAPTKALLADPSPLVRGAAVWALSQLTPPDDFAALAKATTETDP
KVLGEWRRS