Protein Info for A4249_RS09810 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: family 43 glycosylhydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 486 transmembrane" amino acids 20 to 37 (18 residues), see Phobius details amino acids 176 to 196 (21 residues), see Phobius details PF04616: Glyco_hydro_43" amino acids 2 to 272 (271 residues), 296.4 bits, see alignment E=2.3e-92 PF17851: GH43_C2" amino acids 299 to 466 (168 residues), 51.2 bits, see alignment E=1.4e-17

Best Hits

KEGG orthology group: None (inferred from 72% identity to cja:CJA_3007)

Predicted SEED Role

"Beta-xylosidase (EC 3.2.1.37)" in subsystem Xylose utilization (EC 3.2.1.37)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.37

Use Curated BLAST to search for 3.2.1.37

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I2M1 at UniProt or InterPro

Protein Sequence (486 amino acids)

>A4249_RS09810 family 43 glycosylhydrolase (Brevundimonas sp. GW460-12-10-14-LB2)
MNPIVAGDHPDPTILKDGDTYYITFSSFLSYPGLVIWTSKDLVNWSPIGPALHKPLGDVW
AVDLVKHQGRYFIYIPANPTGKGWSIFTIWADDIAGPWSDPVDMKIEGCIDPGHVVGEDG
RRYLFVNGIRKVRLTDDGLATDGAVEPAYDPWRYPDDWITENFAPEGPKLLRRGDWFYLV
TAVGGTAGPVTGHMVIAARSRSVHGPWENCPQNPLVRTQSVDEPWWSRGHATLVEGPAGD
WWMVYHGYENGFRTLGRQTLLEPVEWTADGWFRAMGGDLSRSLAKPRAREASPAGAALSD
DFSHDRMGVKWSFHQPKADAANRLTRADRSLRLEGQGRSPADSSPLACLVRDRSYRVEID
LALSGEAEAGLLLFYNHKAFVGLGFDGRVIKSYQYAEEQTWAAIPAVTRELKLKIDNDEN
VVTYHYSLDRGATWVRHPTRMEVSGLNHNVFGGFLSLRPAIYCAGSGAVVLKDFRYAAGN
RRLTAA