Protein Info for A4249_RS08595 in Brevundimonas sp. GW460-12-10-14-LB2
Annotation: ABC transporter ATP-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 39% identical to MLAF_HAEIN: Intermembrane phospholipid transport system ATP-binding protein MlaF (mlaF) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG orthology group: K02065, putative ABC transport system ATP-binding protein (inferred from 84% identity to bsb:Bresu_1454)Predicted SEED Role
"Methionine ABC transporter ATP-binding protein" in subsystem Methionine Biosynthesis or Methionine Degradation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A160HZL7 at UniProt or InterPro
Protein Sequence (258 amino acids)
>A4249_RS08595 ABC transporter ATP-binding protein (Brevundimonas sp. GW460-12-10-14-LB2) MTEAPENLIEVRGLLSQFGERTIHENLDLDLVRGEVLGVVGGSGAGKTVLLNTIIGLKEP EGGSVKVLGYDRATLTDDQSADIERRTGILFQQGALFSSLSVLENVASPLVEHTKLPKAI IYELAELKIAMVGLKPEHHHLKPAELSGGMKKRAGLARALALDPELVFLDEPTAGLDPIG AAAFDDLIRQLADDLGLSVFMITHDLDTLYAICDKVAVLADKRVVEKATVQELEGSDHPW IKEYFLGPRGRAATKSAA