Protein Info for A4249_RS08440 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: TlyA family RNA methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 243 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR00478: TlyA family rRNA methyltransferase/putative hemolysin" amino acids 4 to 234 (231 residues), 206.7 bits, see alignment E=1.5e-65 PF01479: S4" amino acids 4 to 43 (40 residues), 34 bits, see alignment 2e-12 PF01728: FtsJ" amino acids 58 to 240 (183 residues), 121.7 bits, see alignment E=3.5e-39

Best Hits

KEGG orthology group: K06442, putative hemolysin (inferred from 69% identity to bsb:Bresu_1824)

Predicted SEED Role

"RNA binding methyltransferase FtsJ like"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HZN1 at UniProt or InterPro

Protein Sequence (243 amino acids)

>A4249_RS08440 TlyA family RNA methyltransferase (Brevundimonas sp. GW460-12-10-14-LB2)
MKTRIDQLLVARGLFDSRSQARAAIVAGLVLADGVIVRKASEQFSDDIALEAQPAHPWVG
RGALKLDHALTLWPVLVEGRVALDVGASTGGFTEVLLNRGAAKVFAVDVGFGQMHARVSS
DPRVINLERTDARDLTPDVIPQPPSLVVCDASFISLIKVLPVALDLATPGADLVTLVKPQ
FEADGPGGGKKGVIKDARAHAAAVERVRDWLEALGWAVQATTESPITGGDGNLEFLLWAK
KPG