Protein Info for A4249_RS06280 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: DUF4142 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF13628: DUF4142" amino acids 58 to 193 (136 residues), 110.4 bits, see alignment E=8.5e-36

Best Hits

KEGG orthology group: K08995, putative membrane protein (inferred from 62% identity to bsb:Bresu_2503)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NGV8 at UniProt or InterPro

Protein Sequence (198 amino acids)

>A4249_RS06280 DUF4142 domain-containing protein (Brevundimonas sp. GW460-12-10-14-LB2)
MKYLAIASVASLALLAACNQGGDSAAQNTGEAVNATQDATSGVVGQTSAMTMGANTVDGF
VTGLGTGNMYELEAAKIAAAKSKNADVKALAAMITKDHTAAGEKLAAAQATAAPNVAIPT
TLDERRKGLIDNLNAATPDDFDKVYLDQQVAAHNETLTLLNGFADNTEAPALATLARELV
TPVTAHRDRARTLLDAMK