Protein Info for A4249_RS04695 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: rod shape-determining protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 TIGR00904: cell shape determining protein, MreB/Mrl family" amino acids 10 to 335 (326 residues), 507.4 bits, see alignment E=8e-157 PF06723: MreB_Mbl" amino acids 10 to 338 (329 residues), 491.2 bits, see alignment E=2.9e-151 PF00022: Actin" amino acids 47 to 202 (156 residues), 33.1 bits, see alignment E=6.2e-12 PF00012: HSP70" amino acids 102 to 328 (227 residues), 41 bits, see alignment E=2.1e-14 PF14450: FtsA" amino acids 159 to 318 (160 residues), 39.8 bits, see alignment E=1.3e-13

Best Hits

Swiss-Prot: 92% identical to MREB_CAUVN: Cell shape-determining protein MreB (mreB) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: K03569, rod shape-determining protein MreB and related proteins (inferred from 99% identity to bsb:Bresu_2299)

Predicted SEED Role

"Rod shape-determining protein MreB" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NEV3 at UniProt or InterPro

Protein Sequence (346 amino acids)

>A4249_RS04695 rod shape-determining protein (Brevundimonas sp. GW460-12-10-14-LB2)
MSFSLFGAISNDIAMDLGTANTLIYMKGKGIVLNEPSVVALRNVGGRKVVHAVGIEAKQM
LGRTPGHMEAIRPMRDGVIADFEVAEEMIKHFIRKVHNRKGFVNPKIIVCVPSGATAVER
RAINDSCLNASARRVGLIDEPMAAAIGAGLPIHEPTGSMVVDIGGGTTEVAVLSLSGIVY
SRSVRVGGDKMDDSIISYMRRNHNLLIGETTAERIKKDIGTARIPADGEGLSIEVKGRDL
MQGVPREVRISERQAAEALAEPVTQIIEAVKVALEATPPELAADIADKGIMLTGGGALLR
GLDVEIRDHTGLPVSVADDPLSCVAIGCGRVLEHPRWMKGVLDSAL