Protein Info for A4249_RS03575 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 291 transmembrane" amino acids 227 to 246 (20 residues), see Phobius details PF00126: HTH_1" amino acids 4 to 62 (59 residues), 62.8 bits, see alignment E=2.3e-21 PF03466: LysR_substrate" amino acids 87 to 280 (194 residues), 99.8 bits, see alignment E=1.5e-32

Best Hits

KEGG orthology group: None (inferred from 47% identity to npp:PP1Y_Mpl209)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HXP7 at UniProt or InterPro

Protein Sequence (291 amino acids)

>A4249_RS03575 LysR family transcriptional regulator (Brevundimonas sp. GW460-12-10-14-LB2)
MYDWDDLRIFIAAARAGSLGGAAQRLGVDAATVGRRVARLESALKSTLVVRSTTGLQLTA
AGAQLLDIGLEAESAMEAVGRVTQPDAPAGVVRVSASEGFGVTLMAPALPALRLAHPGLR
IELAATSGFLSPTRREVDMAITLAAPHAARLIVEPLTPYQLALYASPDHLHRNGVPKTVD
DLSRFDIVGYIDDLIYAPELRYLDEVQPGLAPHVASSSIRAQREIIAAGGGVGVLPCFLA
EGLVRVLPSILIERRFWLATHRDVHDTARLRTVRSWLKTLCQEQQSSLRPF