Protein Info for A4249_RS02665 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: MBL fold metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 361 PF00753: Lactamase_B" amino acids 49 to 267 (219 residues), 102.4 bits, see alignment E=1.7e-33

Best Hits

KEGG orthology group: None (inferred from 67% identity to bsb:Bresu_2653)

Predicted SEED Role

"Metallo-beta-lactamase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161IXI4 at UniProt or InterPro

Protein Sequence (361 amino acids)

>A4249_RS02665 MBL fold metallo-hydrolase (Brevundimonas sp. GW460-12-10-14-LB2)
MADGTAPATAAKDGRGLTYPFDAVPGAGEAIEVAPGVLWLRFALPFQLDHVNVYAIRDVG
GWVVVDTGLKTAATIAAWETALDATLGGRPVTRLICTHMHPDHIGLAGWLCERSGAPLLM
SRLEYVTARMLMAEEAGDAPADGERYYRAAGWSDEQIARWRADYGGFGKGVATMPRSYLR
LSDGDVVQIDGDDWSVVVGSGHSPEHVCLWRRSDDVFIAGDQILPRISSNVSVWSTEPEA
DPLGDWMGSLDKLRALLPEGAFVLPAHGEPFYGVHARLDALKRGHEVALKRLERTLRQPS
RVVDGFSAVFGRVVGDGVLGMATGEAQAHLNYLERRGRAQRTRDESGVDWWSAVAQDEET
T