Protein Info for A4249_RS00235 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: metalloregulator ArsR/SmtB family transcription factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 110 PF12840: HTH_20" amino acids 26 to 74 (49 residues), 30.8 bits, see alignment E=2.3e-11 PF01022: HTH_5" amino acids 28 to 73 (46 residues), 50.1 bits, see alignment E=2e-17

Best Hits

Swiss-Prot: 51% identical to YGAV_ECOLI: Probable HTH-type transcriptional regulator YgaV (ygaV) from Escherichia coli (strain K12)

KEGG orthology group: K03892, ArsR family transcriptional regulator (inferred from 68% identity to ccs:CCNA_02957)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168MWN0 at UniProt or InterPro

Protein Sequence (110 amino acids)

>A4249_RS00235 metalloregulator ArsR/SmtB family transcription factor (Brevundimonas sp. GW460-12-10-14-LB2)
MIDLQTIGLERFQASAGEAAALLRALSNEKRLMILCQLGEGEMAVGQLLPQVGLSQSALS
QHLAKLRDEALVSTRRDGTTIFYRIADPAVLKVIAVLAEIYCPPVSSEKA