Protein Info for b2870 in Escherichia coli BW25113

Name: ygeW
Annotation: hypothetical protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 396 TIGR03316: knotted carbamoyltransferase YgeW" amino acids 6 to 394 (389 residues), 675.3 bits, see alignment E=1.3e-207 PF02729: OTCace_N" amino acids 22 to 178 (157 residues), 86.7 bits, see alignment E=1.7e-28 PF00185: OTCace" amino acids 187 to 373 (187 residues), 107 bits, see alignment E=1e-34

Best Hits

Swiss-Prot: 100% identical to YGEW_ECOL6: Putative carbamoyltransferase YgeW (ygeW) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 100% identity to eco:b2870)

Predicted SEED Role

"Aspartate/ornithine carbamoyltransferase family protein protein YgeW"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q46803 at UniProt or InterPro

Protein Sequence (396 amino acids)

>b2870 hypothetical protein (NCBI) (Escherichia coli BW25113)
MMKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNS
GLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIG
IRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQCDIDHPTQSMADLAWLREHF
GSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVA
KNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEERTELLRANDHEGLKALEKQC
LAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKE
ASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK