Protein Info for b4359 in Escherichia coli BW25113

Name: mdoB
Annotation: phosphoglycerol transferase I (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 763 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 28 to 47 (20 residues), see Phobius details amino acids 59 to 74 (16 residues), see Phobius details amino acids 77 to 98 (22 residues), see Phobius details amino acids 110 to 128 (19 residues), see Phobius details PF00884: Sulfatase" amino acids 163 to 446 (284 residues), 85.9 bits, see alignment E=1.6e-28

Best Hits

Swiss-Prot: 100% identical to OPGB_ECOLI: Phosphoglycerol transferase I (mdoB) from Escherichia coli (strain K12)

KEGG orthology group: K01002, phosphoglycerol transferase [EC: 2.7.8.20] (inferred from 100% identity to eco:b4359)

MetaCyc: 100% identical to phosphoglycerol transferase I (Escherichia coli K-12 substr. MG1655)
Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase. [EC: 2.7.8.20]

Predicted SEED Role

"Phosphoglycerol transferase I (EC 2.7.8.20)" (EC 2.7.8.20)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P39401 at UniProt or InterPro

Protein Sequence (763 amino acids)

>b4359 phosphoglycerol transferase I (VIMSS) (Escherichia coli BW25113)
MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNITLFASDYFTGDGINDAV
LYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRRHHPHHFGYSLLALLLALG
SVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDPKLNLVYIYGESLERTYFDNE
AFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVASQCGIPLFAPFEGNASASVSSFF
PQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKSHGFDHLYGSEELKSVVADPHYRND
WGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVDTHHPDGFISRTCNRKKYDFDGKPNQS
FSAVSCSQENIATFINKIKASPWFKDTVIVVSSDHLAMNNTAWKYLNKQDRNNLFFVIRG
DKPQQETLAVKRNTMDNGATVLDILGGDNYLGLGRSSLSGQSMSEIFLNIKEKTLAWKPD
IIRLWKFPKEMKEFTIDQQKNMIAFSGSHFRLPLLLRVSDKRVEPLPESEYSAPLRFQLA
DFAPRDNFVWVDRCYKMAQLWAPELALSTDWCVSQGQLGGQQIVQHVDKTTWQGKTAFKD
TVIDMARYKGNVDTLKIVDNDIRYKADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQL
GDEVKIEYKHPLPKKFDLVITAKAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNP
TDADTLVIVPPEPVSTNEGNILGHSPRKLGIGMVEIKVVEREG