Protein Info for b4231 in Escherichia coli BW25113

Name: yjfF
Annotation: putative transport system permease protein (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 43 to 76 (34 residues), see Phobius details amino acids 88 to 109 (22 residues), see Phobius details amino acids 116 to 134 (19 residues), see Phobius details amino acids 161 to 180 (20 residues), see Phobius details amino acids 212 to 232 (21 residues), see Phobius details amino acids 247 to 278 (32 residues), see Phobius details amino acids 291 to 315 (25 residues), see Phobius details PF02653: BPD_transp_2" amino acids 35 to 304 (270 residues), 131.5 bits, see alignment E=1.7e-42

Best Hits

Swiss-Prot: 100% identical to YJFF_ECOLI: Inner membrane ABC transporter permease protein YjfF (yjfF) from Escherichia coli (strain K12)

KEGG orthology group: K02057, simple sugar transport system permease protein (inferred from 100% identity to eco:b4231)

MetaCyc: 100% identical to galactofuranose ABC transporter putative membrane subunit YjtF (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-491 [EC: 7.5.2.9]; 7.5.2.9 [EC: 7.5.2.9]

Predicted SEED Role

"Putative sugar ABC transport system, permease protein YjfF"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P37772 at UniProt or InterPro

Protein Sequence (331 amino acids)

>b4231 putative transport system permease protein (VIMSS) (Escherichia coli BW25113)
MIKRNLPLMITIGVFVLGYLYCLTQFPGFASTRVICNILTDNAFLGIIAVGMTFVILSGG
IDLSVGSVIAFTGVFLAKVIGDFGLSPLLAFPLVLVMGCAFGAFMGLLIDALKIPAFIIT
LAGMFFLRGVSYLVSEESIPINHPIYDTLSSLAWKIPGGGRLSAMGLLMLAVVVIGIFLA
HRTRFGNQVYAIGGNATSANLMGISTRSTTIRIYMLSTGLATLAGIVFSIYTQAGYALAG
VGVELDAIASVVIGGTLLSGGVGTVLGTLFGVAIQGLIQTYINFDGTLSSWWTKIAIGIL
LFIFIALQRGLTVLWENRQSSPVTRVNIAQQ