Protein Info for b4141 in Escherichia coli BW25113

Name: yjeH
Annotation: predicted transporter (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 43 to 63 (21 residues), see Phobius details amino acids 87 to 109 (23 residues), see Phobius details amino acids 118 to 137 (20 residues), see Phobius details amino acids 147 to 166 (20 residues), see Phobius details amino acids 186 to 208 (23 residues), see Phobius details amino acids 220 to 242 (23 residues), see Phobius details amino acids 262 to 286 (25 residues), see Phobius details amino acids 318 to 336 (19 residues), see Phobius details amino acids 342 to 363 (22 residues), see Phobius details amino acids 373 to 405 (33 residues), see Phobius details PF13520: AA_permease_2" amino acids 8 to 390 (383 residues), 103.3 bits, see alignment E=1.6e-33 PF00324: AA_permease" amino acids 21 to 414 (394 residues), 39 bits, see alignment E=4.3e-14

Best Hits

Swiss-Prot: 100% identical to YJEH_ECOLI: L-methionine/branched-chain amino acid exporter YjeH (yjeH) from Escherichia coli (strain K12)

KEGG orthology group: K03294, basic amino acid/polyamine antiporter, APA family (inferred from 100% identity to eco:b4141)

MetaCyc: 100% identical to L-methionine/branched chain amino acid exporter (Escherichia coli K-12 substr. MG1655)
RXN0-7050; TRANS-RXN-281; TRANS-RXN-282; TRANS-RXN0-270

Predicted SEED Role

"Putative permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P39277 at UniProt or InterPro

Protein Sequence (418 amino acids)

>b4141 predicted transporter (NCBI) (Escherichia coli BW25113)
MSGLKQELGLAQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWAWPVLIILVFPIAIVFA
ILGRHYPSAGGVAHFVGMAFGSRLERVTGWLFLSVIPVGLPAALQIAAGFGQAMFGWHSW
QLLLAELGTLALVWYIGTRGASSSANLQTVIAGLIVALIVAIWWAGDIKPANIPFPAPGN
IELTGLFAALSVMFWCFVGLEAFAHLASEFKNPERDFPRALMIGLLLAGLVYWGCTVVVL
HFDAYGEKMAAAASLPKIVVQLFGVGALWIACVIGYLACFASLNIYIQSFARLVWSQAQH
NPDHYLARLSSRHIPNNALNAVLGCCVVSTLVIHALEINLDALIIYANGIFIMIYLLCML
AGCKLLQGRYRLLAVVGGLLCVLLLAMVGWKSLYALIMLAGLWLLLPKRKTPENGITT