Protein Info for b3902 in Escherichia coli BW25113

Name: rhaD
Annotation: rhamnulose-1-phosphate aldolase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 TIGR02624: rhamnulose-1-phosphate aldolase" amino acids 1 to 272 (272 residues), 469 bits, see alignment E=2.2e-145 PF00596: Aldolase_II" amino acids 13 to 238 (226 residues), 79.7 bits, see alignment E=1.3e-26

Best Hits

Swiss-Prot: 100% identical to RHAD_ECOLI: Rhamnulose-1-phosphate aldolase (rhaD) from Escherichia coli (strain K12)

KEGG orthology group: K01629, rhamnulose-1-phosphate aldolase [EC: 4.1.2.19] (inferred from 100% identity to eco:b3902)

MetaCyc: 100% identical to rhamnulose-1-phosphate aldolase (Escherichia coli K-12 substr. MG1655)
Rhamnulose-1-phosphate aldolase. [EC: 4.1.2.19]

Predicted SEED Role

"Rhamnulose-1-phosphate aldolase (EC 4.1.2.19)" in subsystem L-rhamnose utilization (EC 4.1.2.19)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.2.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P32169 at UniProt or InterPro

Protein Sequence (274 amino acids)

>b3902 rhamnulose-1-phosphate aldolase (NCBI) (Escherichia coli BW25113)
MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAPYHDNFHQQPRYIPLSQ
PMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGYHILWGLTNEAVPTSELPA
HFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQLWEGSTECLVVFPDGV
GILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAQVLVK
VYSMGGMKQTISREELIALGKRFGVTPLASALAL