Protein Info for b3576 in Escherichia coli BW25113

Name: yiaL
Annotation: hypothetical protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 155 TIGR00022: YhcH/YjgK/YiaL family protein" amino acids 1 to 153 (153 residues), 222 bits, see alignment E=1.6e-70 PF04074: DUF386" amino acids 1 to 150 (150 residues), 142.6 bits, see alignment E=4.8e-46

Best Hits

Swiss-Prot: 100% identical to YIAL_ECOLI: Protein YiaL (yiaL) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b3576)

Predicted SEED Role

"Putative sugar isomerase involved in processing of exogenous sialic acid" in subsystem Sialic Acid Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P37673 at UniProt or InterPro

Protein Sequence (155 amino acids)

>b3576 hypothetical protein (NCBI) (Escherichia coli BW25113)
MIFGHIAQPNPCRLPAAIEKALDFLRATDFNALEPGVVEIDGKNIYTQIIDLTTREAVVN
RPEVHRRYIDIQFLAWGEEKIGIAIDTGNNKVSESLLEQRNIIFYHDSEHESFIEMIPGS
YAIFFPQDVHRPGCIMQTASEIRKIVVKVALTALN