Protein Info for b3564 in Escherichia coli BW25113

Name: xylB
Annotation: xylulokinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 484 PF00370: FGGY_N" amino acids 1 to 240 (240 residues), 302.7 bits, see alignment E=2.2e-94 TIGR01312: xylulokinase" amino acids 3 to 477 (475 residues), 653.6 bits, see alignment E=8e-201 PF02782: FGGY_C" amino acids 249 to 436 (188 residues), 110.4 bits, see alignment E=1e-35

Best Hits

Swiss-Prot: 100% identical to XYLB_ECOLI: Xylulose kinase (xylB) from Escherichia coli (strain K12)

KEGG orthology group: K00854, xylulokinase [EC: 2.7.1.17] (inferred from 100% identity to eco:b3564)

MetaCyc: 100% identical to xylulokinase (Escherichia coli K-12 substr. MG1655)
Xylulokinase. [EC: 2.7.1.17]; 2.7.1.- [EC: 2.7.1.17]

Predicted SEED Role

"Xylulose kinase (EC 2.7.1.17)" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization or Xylose utilization (EC 2.7.1.17)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P09099 at UniProt or InterPro

Protein Sequence (484 amino acids)

>b3564 xylulokinase (NCBI) (Escherichia coli BW25113)
MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALG
DQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITG
NLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRMTGEFASDMSDAAGTMWLDVA
KRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDW
AAKLTGLSNVPALIAAAQQADESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNE
LARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSEYWRQMLADISGQQLDYRTGG
DVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
PLMA