Protein Info for b3073 in Escherichia coli BW25113

Name: ygjG
Annotation: putrescine:2-oxoglutaric acid aminotransferase, PLP-dependent (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03372: putrescine aminotransferase
  • amino acids 8 to 449 (442 residues), 977.1 bits, E=5.2e-299
• PF00202: Aminotran_3
  • amino acids 74 to 448 (375 residues), 341 bits, E=4.1e-106

Best Hits

Swiss-Prot: 100% identical to PAT_ECOLI: Putrescine aminotransferase (patA) from Escherichia coli (strain K12)

KEGG orthology group: K09251, putrescine aminotransferase [EC: 2.6.1.82] (inferred from 100% identity to eco:b3073)

MetaCyc: 100% identical to putrescine aminotransferase (Escherichia coli K-12 substr. MG1655)
Putrescine aminotransferase. [EC: 2.6.1.82]; 2.6.1.82 [EC: 2.6.1.82]; Diamine transaminase. [EC: 2.6.1.82, 2.6.1.29]

Predicted SEED Role

"Putrescine aminotransferase (EC 2.6.1.82)" in subsystem Arginine and Ornithine Degradation (EC 2.6.1.82)

MetaCyc Pathways

• superpathway of L-arginine and L-ornithine degradation (13/13 steps found)
• superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation (11/11 steps found)
• superpathway of ornithine degradation (8/8 steps found)
• L-lysine degradation I (7/7 steps found)
• L-lysine degradation X (5/6 steps found)
• putrescine degradation I (2/2 steps found)
• superpathway of L-lysine degradation (14/43 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.29 or 2.6.1.82

Sequence Analysis Tools

See P42588 at UniProt or InterPro

Protein Sequence (459 amino acids)

>b3073 putrescine:2-oxoglutaric acid aminotransferase, PLP-dependent (RefSeq) (Escherichia coli BW25113)
MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAG
GDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQE
LLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAF
HGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPI
QGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAK
ALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAE
QKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLN
NAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA