Protein Info for b2766 in Escherichia coli BW25113

Name: ygcN
Annotation: orf, hypothetical protein (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 PF01494: FAD_binding_3" amino acids 4 to 183 (180 residues), 34.6 bits, see alignment E=7e-12 PF01134: GIDA" amino acids 6 to 36 (31 residues), 24.6 bits, see alignment (E = 7.1e-09) PF07992: Pyr_redox_2" amino acids 6 to 159 (154 residues), 30.3 bits, see alignment E=1.7e-10 PF01266: DAO" amino acids 6 to 58 (53 residues), 41.1 bits, see alignment 9.2e-14 PF00890: FAD_binding_2" amino acids 6 to 37 (32 residues), 30.5 bits, see alignment (E = 1.3e-10) PF12831: FAD_oxidored" amino acids 6 to 151 (146 residues), 36.1 bits, see alignment E=2.7e-12 PF03486: HI0933_like" amino acids 6 to 47 (42 residues), 28.5 bits, see alignment 3.7e-10 PF13450: NAD_binding_8" amino acids 9 to 40 (32 residues), 29.5 bits, see alignment (E = 4.1e-10) PF21162: ETFQO_UQ-bd" amino acids 176 to 273 (98 residues), 28.7 bits, see alignment E=9.1e-10

Best Hits

Swiss-Prot: 100% identical to YGCN_ECOLI: Probable electron transfer flavoprotein-quinone oxidoreductase YgcN (ygcN) from Escherichia coli (strain K12)

KEGG orthology group: K00313, electron transfer flavoprotein-quinone oxidoreductase [EC: 1.5.5.-] (inferred from 100% identity to eco:b2766)

Predicted SEED Role

"Probable electron transfer flavoprotein-quinone oxidoreductase YgcN (EC 1.5.5.-)" (EC 1.5.5.-)

Isozymes

Compare fitness of predicted isozymes for: 1.5.5.-

Use Curated BLAST to search for 1.5.5.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q46904 at UniProt or InterPro

Protein Sequence (423 amino acids)

>b2766 orf, hypothetical protein (VIMSS) (Escherichia coli BW25113)
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQ
FHLTAPLERRITHESLSLLTPDGVTTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECI
PGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIK
EVLSLETSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALR
SCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQH
VPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSL
RCL