Protein Info for b2382 in Escherichia coli BW25113

Name: ypdC
Annotation: predicted DNA-binding protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 92 to 109 (18 residues), see Phobius details PF12833: HTH_18" amino acids 204 to 281 (78 residues), 73.8 bits, see alignment E=1.1e-24 PF00165: HTH_AraC" amino acids 247 to 279 (33 residues), 40.1 bits, see alignment 2.9e-14

Best Hits

Swiss-Prot: 100% identical to YPDC_ECOLI: Uncharacterized HTH-type transcriptional regulator YpdC (ypdC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b2382)

Predicted SEED Role

"Putative HTH-type transcriptional regulator ypdC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P77396 at UniProt or InterPro

Protein Sequence (285 amino acids)

>b2382 predicted DNA-binding protein (NCBI) (Escherichia coli BW25113)
MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSLCIDFPRLDIVLRGEYG
NLLEAKQQRLVEGEMLFIPARAANLPVNNKPVMLLSLVFAPTWLGLSFYDSRTTSLLHPA
RQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSLLHLCRSVVNMPPGNSQPRGD
FLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLFAQHGTMRFIEYVRWVRMAKARM
ILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTPGEYSARFQG