Protein Info for b2361 in Escherichia coli BW25113

Name: b2361
Annotation: orf, hypothetical protein (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.

Best Hits

Swiss-Prot: 100% identical to YFDR_ECOLI: Uncharacterized protein YfdR (yfdR) from Escherichia coli (strain K12)

KEGG orthology group: K06952, (no description) (inferred from 100% identity to eco:b2361)

MetaCyc: 100% identical to CPS-53 (KpLE1) prophage; 5'-deoxynucleotidase (Escherichia coli K-12 substr. MG1655)
RXN0-3741 [EC: 3.1.3.89]

Predicted SEED Role

"Hypothetical protein yfdR"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.89

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P76514 at UniProt or InterPro

Protein Sequence (178 amino acids)

>b2361 orf, hypothetical protein (VIMSS) (Escherichia coli BW25113)
MSFIKTFSGKHFYYDKINKDDIVINDIAVSLSNICRFAGHLSHFYSVAQHAVLCSQLVPQ
EFAFEALMHDATEAYCQDIPAPLKRLLPDYKRMEEKIDAVIREKYGLPPVMSTPVKYADL
IMLATERRDLGLDDGSFWPVLEGIPATEMFNVIPLAPGHAYGMFMERFNDLSELRKCA