Protein Info for b2166 in Escherichia coli BW25113

Name: yeiC
Annotation: predicted kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00294: PfkB
  • amino acids 5 to 295 (291 residues), 234.8 bits, E=7.6e-74

Best Hits

Swiss-Prot: 100% identical to PSUK_ECOLI: Pseudouridine kinase (psuK) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b2166)

MetaCyc: 88% identical to pseudouridine kinase (Escherichia coli UTI89)
Pseudouridine kinase. [EC: 2.7.1.83]

Predicted SEED Role

"Pseudouridine kinase (EC 2.7.1.83)" (EC 2.7.1.83)

MetaCyc Pathways

• pseudouridine degradation (2/2 steps found)

KEGG Metabolic Maps

• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.83

Sequence Analysis Tools

See P30235 at UniProt or InterPro

Protein Sequence (313 amino acids)

>b2166 predicted kinase (NCBI) (Escherichia coli BW25113)
MREKDYVVIIGSANIDVAGYSHESLNYADSNPGKIKFTPGGVGRNIAQNLALLGNKAWLL
SAVGSDFYGQSLLTQTNQSGVYVDKCLIVPGENTSSYLSLLDNTGEMLVAINDMNISNAI
TAEYLAQHGEFIQRAKVIVADCNISEEALAWILDNAANVPVFVDPVSAWKCVKVRDRLNQ
IHTLKPNRLEAETLSGIALSGREDVAKVAAWFHQHGLNRLVLSMGGDGVYYSDISGESGW
SAPIKTNVINVTGAGDAMMAGLASCWVDGMPFAESVRFAQGCSSMALSCEYTNNPDLSIA
NVISLVENAECLN