Protein Info for b1429 in Escherichia coli BW25113

Name: tehA
Annotation: potassium-tellurite ethidium and proflavin transporter (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 transmembrane" amino acids 7 to 30 (24 residues), see Phobius details amino acids 40 to 64 (25 residues), see Phobius details amino acids 76 to 98 (23 residues), see Phobius details amino acids 103 to 125 (23 residues), see Phobius details amino acids 142 to 161 (20 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details amino acids 196 to 218 (23 residues), see Phobius details amino acids 230 to 249 (20 residues), see Phobius details amino acids 256 to 275 (20 residues), see Phobius details amino acids 285 to 309 (25 residues), see Phobius details PF03595: SLAC1" amino acids 8 to 305 (298 residues), 149.9 bits, see alignment E=5.1e-48 TIGR00816: C4-dicarboxylate transporter/malic acid transport protein" amino acids 9 to 312 (304 residues), 375.3 bits, see alignment E=1.4e-116

Best Hits

Swiss-Prot: 100% identical to TEHA_ECOLI: Tellurite resistance protein TehA (tehA) from Escherichia coli (strain K12)

KEGG orthology group: K03304, tellurite resistance/dicarboxylate transporter, TDT family (inferred from 100% identity to eco:b1429)

MetaCyc: 100% identical to tellurite resistance protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-539

Predicted SEED Role

"Tellurite resistance protein TehA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P25396 at UniProt or InterPro

Protein Sequence (330 amino acids)

>b1429 potassium-tellurite ethidium and proflavin transporter (NCBI) (Escherichia coli BW25113)
MQSDKVLNLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTSAFI
ARLIRFPHSVLAEVRHPVLSSFVSLFPATTMLVAIGFVPWFRPLAVCLFSFGVVVQLAYA
AWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALGYTDAGLVFLGAGVFSWLSLE
PVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDTLAKMLFGYGLLQLLF
MLRLMPWYLSQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAI
LLIRTFALLMQGKLLVRTERAVLMKAEDKE