Protein Info for b1333 in Escherichia coli BW25113

Name: uspE
Annotation: stress-induced protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 PF00582: Usp" amino acids 3 to 146 (144 residues), 74.7 bits, see alignment E=5.7e-25 amino acids 174 to 300 (127 residues), 59.5 bits, see alignment E=2.7e-20

Best Hits

Swiss-Prot: 100% identical to USPE_ECOLI: Universal stress protein E (uspE) from Escherichia coli (strain K12)

KEGG orthology group: K14055, universal stress protein E (inferred from 100% identity to eco:b1333)

Predicted SEED Role

"Universal stress protein E" in subsystem Universal stress protein family

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0AAC0 at UniProt or InterPro

Protein Sequence (316 amino acids)

>b1333 stress-induced protein (NCBI) (Escherichia coli BW25113)
MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDFSYEMTTLLSPDERTAM
RQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQEVISGGHDLVLKMAHQHD
RLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAVNLASEEPYHNALNEKLVKET
IELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYNDAIRGQHLLAMKALRQKFGINE
NMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGISAAFLGNTAEQVIDHLRCDLLVIK
PDQYQTPVELDDEEDD