Protein Info for b0783 in Escherichia coli BW25113

Name: moaC
Annotation: molybdenum cofactor biosynthesis protein C (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00581: molybdenum cofactor biosynthesis protein C
  • amino acids 4 to 152 (149 residues), 245.9 bits, E=5.7e-78
• PF01967: MoaC
  • amino acids 15 to 150 (136 residues), 197.6 bits, E=4.1e-63

Best Hits

Swiss-Prot: 100% identical to MOAC_ECO27: Cyclic pyranopterin monophosphate synthase (moaC) from Escherichia coli O127:H6 (strain E2348/69 / EPEC)

KEGG orthology group: K03637, molybdenum cofactor biosynthesis protein C (inferred from 100% identity to eco:b0783)

MetaCyc: 100% identical to cyclic pyranopterin monophosphate synthase (Escherichia coli K-12 substr. MG1655)
RXN-17809 [EC: 4.6.1.17]

Predicted SEED Role

"Molybdenum cofactor biosynthesis protein MoaC" in subsystem Molybdenum cofactor biosynthesis

MetaCyc Pathways

• molybdopterin biosynthesis (6/6 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.6.1.17

Sequence Analysis Tools

See P0A738 at UniProt or InterPro

Protein Sequence (161 amino acids)

>b0783 molybdenum cofactor biosynthesis protein C (NCBI) (Escherichia coli BW25113)
MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARI
AGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAAS
VAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD