Protein Info for b0598 in Escherichia coli BW25113

Name: cstA
Annotation: carbon starvation protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 701 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 32 to 52 (21 residues), see Phobius details amino acids 92 to 111 (20 residues), see Phobius details amino acids 117 to 138 (22 residues), see Phobius details amino acids 159 to 183 (25 residues), see Phobius details amino acids 191 to 211 (21 residues), see Phobius details amino acids 221 to 240 (20 residues), see Phobius details amino acids 256 to 276 (21 residues), see Phobius details amino acids 285 to 305 (21 residues), see Phobius details amino acids 325 to 345 (21 residues), see Phobius details amino acids 370 to 392 (23 residues), see Phobius details amino acids 399 to 421 (23 residues), see Phobius details amino acids 441 to 458 (18 residues), see Phobius details amino acids 470 to 490 (21 residues), see Phobius details amino acids 515 to 534 (20 residues), see Phobius details amino acids 548 to 571 (24 residues), see Phobius details amino acids 578 to 598 (21 residues), see Phobius details amino acids 648 to 670 (23 residues), see Phobius details PF02554: CstA" amino acids 32 to 403 (372 residues), 581.2 bits, see alignment E=8.5e-179 PF13722: CstA_5TM" amino acids 469 to 596 (128 residues), 138.8 bits, see alignment E=1.1e-44

Best Hits

Swiss-Prot: 100% identical to CSTA_ECOLI: Peptide transporter CstA (cstA) from Escherichia coli (strain K12)

KEGG orthology group: K06200, carbon starvation protein (inferred from 100% identity to eco:b0598)

MetaCyc: 100% identical to pyruvate transporter CstA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-335

Predicted SEED Role

"Carbon starvation protein A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P15078 at UniProt or InterPro

Protein Sequence (701 amino acids)

>b0598 carbon starvation protein (NCBI) (Escherichia coli BW25113)
MNKSGKYLVWTVLSVMGAFALGYIALNRGEQINALWIVVASVCIYLIAYRFYGLYIAKNV
LAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPLVGPVLAAQMGYLPGMIWL
LAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAGVIALVACFMIMVIILAVLAM
IVVKALTHSPWGTYTVAFTIPLALFMGIYLRYLRPGRIGEVSVIGLVFLIFAIISGGWVA
ESPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLLAPRDYLSTFLKIGTIVGLAVGILI
MRPTLTMPALTKFVDGTGPVWTGNLFPFLFITIACGAVSGFHALISSGTTPKMLANEGQA
CFIGYGGMLMESFVAIMALVSACIIDPGVYFAMNSPMAVLAPAGTADVVASAAQVVSSWG
FSITPDTLNQIASEVGEQSIISRAGGAPTLAVGMAYILHGALGGMMDVAFWYHFAILFEA
LFILTAVDAGTRAARFMLQDLLGVVSPGLKRTDSLPANLLATALCVLAWGYFLHQGVVDP
LGGINTLWPLFGIANQMLAGMALMLCAVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQK
AFSPDAKVGFLAIANKFQAMIDSGNIPSQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLA
LFSIKTALAALKDPKPTAKETPYEPMPENVEEIVAQAKGAH