Protein Info for b0512 in Escherichia coli BW25113

Name: allB
Annotation: allantoinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03178: allantoinase
  • amino acids 4 to 449 (446 residues), 676 bits, E=1.1e-207
• PF01979: Amidohydro_1
  • amino acids 50 to 431 (382 residues), 65.1 bits, E=7.2e-22

Best Hits

Swiss-Prot: 100% identical to ALLB_ECOBW: Allantoinase (allB) from Escherichia coli (strain K12 / MC4100 / BW2952)

KEGG orthology group: K01466, allantoinase [EC: 3.5.2.5] (inferred from 100% identity to eco:b0512)

MetaCyc: 100% identical to allantoinase (Escherichia coli K-12 substr. MG1655)
Allantoinase. [EC: 3.5.2.5]

Predicted SEED Role

"Allantoinase (EC 3.5.2.5)" in subsystem Allantoin Utilization (EC 3.5.2.5)

MetaCyc Pathways

• allantoin degradation IV (anaerobic) (8/9 steps found)
• allantoin degradation to glyoxylate II (5/5 steps found)
• allantoin degradation to glyoxylate III (5/5 steps found)
• allantoin degradation to ureidoglycolate II (ammonia producing) (4/4 steps found)
• superpathway of allantoin degradation in plants (6/8 steps found)
• superpathway of purines degradation in plants (13/18 steps found)
• allantoin degradation to glyoxylate I (2/3 steps found)
• superpathway of allantoin degradation in yeast (4/6 steps found)
• allantoin degradation to ureidoglycolate I (urea producing) (1/2 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.2.5

Sequence Analysis Tools

See P77671 at UniProt or InterPro

Protein Sequence (453 amino acids)

>b0512 allantoinase (NCBI) (Escherichia coli BW25113)
MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHT
HISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDA
AQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELG
QPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
CHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGM
WEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMF
GKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGA
RITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ