Protein Info for b0444 in Escherichia coli BW25113

Name: ybaX
Annotation: predicted aluminum resistance protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF06508: QueC
  • amino acids 3 to 213 (211 residues), 277.8 bits, E=5.3e-87
• TIGR00364: queuosine biosynthesis protein QueC
  • amino acids 4 to 206 (203 residues), 295.6 bits, E=7.9e-93

Best Hits

Swiss-Prot: 100% identical to QUEC_ECOBW: 7-cyano-7-deazaguanine synthase (queC) from Escherichia coli (strain K12 / MC4100 / BW2952)

KEGG orthology group: K06920, queuosine biosynthesis protein QueC (inferred from 100% identity to eco:b0444)

MetaCyc: 100% identical to 7-cyano-7-deazaguanine synthase (Escherichia coli K-12 substr. MG1655)
RXN-12093 [EC: 6.3.4.20]

Predicted SEED Role

"Queuosine Biosynthesis QueC ATPase" in subsystem Queuosine-Archaeosine Biosynthesis

MetaCyc Pathways

• preQ₀ biosynthesis (3/4 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.4.20

Sequence Analysis Tools

See P77756 at UniProt or InterPro

Protein Sequence (231 amino acids)

>b0444 predicted aluminum resistance protein (NCBI) (Escherichia coli BW25113)
MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKV
LDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVI
TGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDL
VRNETLTCYNGFKGDGCGHCAACNLRANGLNHYLADKPTVMAAMKQKTGLR