Protein Info for b0390 in Escherichia coli BW25113

Name: aroM
Annotation: hypothetical protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 225 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF07302: AroM" amino acids 5 to 224 (220 residues), 245.8 bits, see alignment E=1.7e-77

Best Hits

Swiss-Prot: 100% identical to AROM_ECOLI: Protein AroM (aroM) from Escherichia coli (strain K12)

KEGG orthology group: K14591, protein AroM (inferred from 100% identity to eco:b0390)

Predicted SEED Role

"AroM protein" in subsystem CBSS-562.2.peg.5158 SK3 including

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0AE28 at UniProt or InterPro

Protein Sequence (225 amino acids)

>b0390 hypothetical protein (NCBI) (Escherichia coli BW25113)
MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREEVMAEYAPEAGEDTILT
LLNDNQLAHVSRRKVERDLQGVVEVLDNQGYDVILLMSTANISSMTARNTIFLEPSRILP
PLVSSIVEDHQVGVIVPVEEMLPVQAQKWQILQKSPVFSLGNPIHDSEQKIIDAGKELLA
KGADVIMLDCLGFHQRHRDLLQKQLDVPVLLSNVLIARLAAELLV