Protein Info for b0062 in Escherichia coli BW25113

Name: araA
Annotation: L-arabinose isomerase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 PF02610: Arabinose_Isome" amino acids 5 to 359 (355 residues), 601.1 bits, see alignment E=7.7e-185 PF11762: Arabinose_Iso_C" amino acids 363 to 476 (114 residues), 155.5 bits, see alignment E=4.6e-50

Best Hits

Swiss-Prot: 100% identical to ARAA_ECOLI: L-arabinose isomerase (araA) from Escherichia coli (strain K12)

KEGG orthology group: K01804, L-arabinose isomerase [EC: 5.3.1.4] (inferred from 100% identity to eco:b0062)

MetaCyc: 100% identical to L-arabinose isomerase (Escherichia coli K-12 substr. MG1655)
L-arabinose isomerase. [EC: 5.3.1.4]

Predicted SEED Role

"L-arabinose isomerase (EC 5.3.1.4)" in subsystem L-Arabinose utilization (EC 5.3.1.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P08202 at UniProt or InterPro

Protein Sequence (500 amino acids)

>b0062 L-arabinose isomerase (NCBI) (Escherichia coli BW25113)
MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEI
TAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDF
MNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCR
FGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMT
PATQIHGKKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQG
YGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAA
EEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLP
KLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDT
RLPAFKDALRWNEVYYGFRR