Protein Info for b0034 in Escherichia coli BW25113

Name: caiF
Annotation: transcriptional regulator of cai operon (VIMSS)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 131 PF07180: CaiF_GrlA" amino acids 5 to 61 (57 residues), 28.2 bits, see alignment E=8.5e-11

Best Hits

Swiss-Prot: 100% identical to CAIF_SHIFL: Transcriptional activatory protein CaiF (caiF) from Shigella flexneri

KEGG orthology group: K08277, transcriptional activator CaiF (inferred from 100% identity to eco:b0034)

Predicted SEED Role

"Transcriptional activatory protein CaiF"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0AE58 at UniProt or InterPro

Protein Sequence (131 amino acids)

>b0034 transcriptional regulator of cai operon (VIMSS) (Escherichia coli BW25113)
MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNTLTYILSEVTEISCEVK
MIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSREKLVGVRKTPRIPAVPLTELNREQK
WQMMLSKSMRR