Protein Info for UW163_RS22295 in Ralstonia solanacearum UW163

Annotation: divalent metal cation transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 442 transmembrane" amino acids 68 to 93 (26 residues), see Phobius details amino acids 114 to 138 (25 residues), see Phobius details amino acids 144 to 163 (20 residues), see Phobius details amino acids 174 to 197 (24 residues), see Phobius details amino acids 217 to 235 (19 residues), see Phobius details amino acids 263 to 286 (24 residues), see Phobius details amino acids 306 to 325 (20 residues), see Phobius details amino acids 354 to 372 (19 residues), see Phobius details amino acids 378 to 399 (22 residues), see Phobius details amino acids 419 to 439 (21 residues), see Phobius details TIGR01197: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family" amino acids 34 to 408 (375 residues), 373 bits, see alignment E=1.1e-115 PF01566: Nramp" amino acids 56 to 414 (359 residues), 456.7 bits, see alignment E=2.8e-141

Best Hits

Swiss-Prot: 96% identical to MNTH_RALSO: Divalent metal cation transporter MntH (mntH) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03322, manganese transport protein (inferred from 96% identity to rso:RS00399)

Predicted SEED Role

"Manganese transport protein MntH" in subsystem Transport of Manganese

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (442 amino acids)

>UW163_RS22295 divalent metal cation transporter (Ralstonia solanacearum UW163)
MFRLPALPRIPTAPFCPSEVRGSVAIPPGLPLWKKLLRFAGPGLLVSVGYMDPGNWATDI
EAGSRYGYSLLFVVLLSSLAAMVLQCLSARLGIVTGKDLARLSRERYRPGAVRVQWLLAE
LSIVACDLAEVLGCALAFHLLLGVPILGGVALTALDTLIVLGLKGKNFRQLEAIVLGLIL
TIGLCYFVELVLIKPHWPSVAGALMPSWQAVSGREPLYLAIGILGATVMPHNLYLHSSVV
QTRVVSETEAARREAVGLSRFDTIASLSLALLVNGAILVLAAAAFHANGHQDVADIQDAH
RLLEPIVGTAVAGVLFGIALLAAGQSSTFTGTIAGQILMEGFLDLRIPCWQRRLITRALA
LIPAFVGVAMLGDHAIGKLLVISQVVLGFQLPFAMFPLIRMTDDRTLMGTFANGRLTSVL
AWCLFVVISVANLWLVWQVLAG