Protein Info for UW163_RS21475 in Ralstonia solanacearum UW163

Annotation: type IV pilin protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 155 transmembrane" amino acids 12 to 37 (26 residues), see Phobius details PF07963: N_methyl" amino acids 11 to 36 (26 residues), 37 bits, see alignment 1.7e-13 TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 14 to 36 (23 residues), 32.8 bits, see alignment 2e-12 PF16732: ComP_DUS" amino acids 37 to 137 (101 residues), 66.4 bits, see alignment E=3.4e-22

Best Hits

KEGG orthology group: K02655, type IV pilus assembly protein PilE (inferred from 88% identity to rso:RSp1287)

Predicted SEED Role

"Type IV pilus biogenesis protein PilE" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (155 amino acids)

>UW163_RS21475 type IV pilin protein (Ralstonia solanacearum UW163)
MKSSQTFPAGRHAAGFTLIELMITLAIVAILVAIAYPSYNNYIMKSHRVDARTALLDLAS
RQERYFALQNNYASTPSALGYAGTAFPLAVQTNGQTYYQLSVQVTGSPGTSTLPGFSASA
VPASPGPQQSDACGTYTINQLGVQGNSGNTTSLCW