Protein Info for UW163_RS21195 in Ralstonia solanacearum UW163

Annotation: VOC family virulence protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 126 PF00903: Glyoxalase" amino acids 5 to 121 (117 residues), 45.3 bits, see alignment E=5.7e-16

Best Hits

Swiss-Prot: 53% identical to GLOD5_MOUSE: Glyoxalase domain-containing protein 5 (Glod5) from Mus musculus

KEGG orthology group: None (inferred from 93% identity to rsl:RPSI07_mp1259)

Predicted SEED Role

"probable ring-cleaving dioxygenase PA0880"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (126 amino acids)

>UW163_RS21195 VOC family virulence protein (Ralstonia solanacearum UW163)
MIDHLDHLVLTATHPDATIDFYTRVLGMQLERFGEGRVAFRFGNQKINLHVRGKEFEPKA
HLPVPGALDLCFIASITLDAVIERLAQADWPIVEGPVLRTGATQPIRSVYVRDPDLNLIE
IAELLG