Protein Info for UW163_RS20480 in Ralstonia solanacearum UW163

Annotation: LacI family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 PF00356: LacI" amino acids 10 to 55 (46 residues), 69.8 bits, see alignment 2.7e-23 PF00532: Peripla_BP_1" amino acids 69 to 315 (247 residues), 71.8 bits, see alignment E=1.4e-23 PF13407: Peripla_BP_4" amino acids 69 to 319 (251 residues), 48.2 bits, see alignment E=2.3e-16 PF13377: Peripla_BP_3" amino acids 176 to 340 (165 residues), 126.4 bits, see alignment E=2.5e-40

Best Hits

KEGG orthology group: K03484, LacI family transcriptional regulator, sucrose operon repressor (inferred from 94% identity to rso:RSp1286)

Predicted SEED Role

"Sucrose operon repressor ScrR, LacI family" in subsystem Sucrose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (340 amino acids)

>UW163_RS20480 LacI family transcriptional regulator (Ralstonia solanacearum UW163)
MVSIPQKRPTIRDVATLAGVSTSTVSRVLNNSGYVKAEVRERIEAVVSRMHYTPSELAKQ
LKSQRSGLIGVIIPKINSYTTSEIVAGISSTLAPLRYQMLLANTANSVAEEVTAYDLFRR
QRVAGVLHLATTVNTDLIDAIREAGLPIVMIGQDASHLGITSVIQNERSAARQITEHLLS
LGHKRVGLVTVGEEDIQVGRERTAGYLDALQARGLPVDPELIICASFRSGAGEEAAERLL
RASGDARCTAILAVTDRLAVGVMACLHDHGLRVPEDMAVAGMGDSDTASMVRPALSTVHY
DYAGTGAEAAQLMLKLWEAEHASQVERIVMPYRLALRRST