Protein Info for UW163_RS20380 in Ralstonia solanacearum UW163

Annotation: sulfurtransferase FdhD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00129: formate dehydrogenase family accessory protein FdhD
  • amino acids 32 to 267 (236 residues), 187.3 bits, E=1.5e-59
• PF02634: FdhD-NarQ
  • amino acids 36 to 269 (234 residues), 206.3 bits, E=3.2e-65

Best Hits

Swiss-Prot: 51% identical to FDHD_BURPS: Sulfur carrier protein FdhD (fdhD) from Burkholderia pseudomallei (strain K96243)

KEGG orthology group: K02379, FdhD protein (inferred from 93% identity to rsl:RPSI07_mp1083)

Predicted SEED Role

"Formate dehydrogenase chain D (EC 1.2.1.2)" in subsystem Formate hydrogenase (EC 1.2.1.2)

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• oxalate degradation VI (1/4 steps found)
• oxalate degradation III (1/5 steps found)
• superpathway of C1 compounds oxidation to CO₂ (4/12 steps found)
• purine nucleobases degradation I (anaerobic) (6/15 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Protein Sequence (272 amino acids)

>UW163_RS20380 sulfurtransferase FdhD (Ralstonia solanacearum UW163)
MTALTRHPAGLPVASTSATRRTRAGAQEDATTAVADEVPVALVFNGITHAVMMASPTDLE
EFALGFALSEGIIDSRADWRGADVDAHPHGLEVHAEIASRCFVRLKERRRALAGPTGCGL
CGIESLQTFEAVPAPLAQPAWVRSLPDAQVLDALKALTAHQPANALTGGLHAAGWVPADG
NGMPAHVLEDVGRHNALDKLIGRLARLGIRPADGFVVMTSRASFELARKCVQTGVPLLAT
ISAPSSLAISHARAGQLTLLAFCRGDSVTRFA