Protein Info for UW163_RS20005 in Ralstonia solanacearum UW163

Annotation: threonine dehydrogenase-zn-dependent dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 611 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 182 to 198 (17 residues), see Phobius details PF07940: Hepar_II_III" amino acids 388 to 585 (198 residues), 123.3 bits, see alignment E=6.1e-40

Best Hits

KEGG orthology group: None (inferred from 94% identity to rsl:RPSI07_mp1004)

Predicted SEED Role

"FIG00974126: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (611 amino acids)

>UW163_RS20005 threonine dehydrogenase-zn-dependent dehydrogenase (Ralstonia solanacearum UW163)
MKRPLVLARTAFALGLPSLARALRYRIGLKLGLNPVRRLRAEIPAGAFFPENRIKTVPDG
LVGGAPEDVAALRYFGWYQPAQHEVPDWHRNPFNGARVTEPSQPWWQIADFDPAVGDIKA
IWEASRFDWALVLAQQAVLGRPQAMTQLNAWLTSWARANPPYLGPNWKCGQEASIRVMHL
AMASLVLGQHLSAAPALIALVRMHLQRIAPTLGYAIAQDNNHGTSEAAALFIGGSWLAAQ
GDPDGRRWQQTGTRWLENRARKLIADDGSFSQHSVMYHRVMLDTYSMAEVWRRHWSLPAF
SAQLQARLGVASNWLYQMIDRATGDAPNLGANDGARLLPLTATDHRDFRPSVQLACALFQ
RADAFGWEGAWSDTLRWLGVPRPEQRLPPARSTHMEAGGYGLLRYGRAFALFNLPHHRHR
PSQADALHVDFWLGGKNLLRDAGSFSYASAESAGYFSGTASHNTVQFDQRDQMPRLGRFL
FGAWLKARDVVPVTQSAEGVTCAAGYRDWQGASHHRALTLNRKSLRVVDRVSGFRRSAVL
RWRLYPGAQLSGNVVQGELGQMTVSADVPIRRIELTSGMESRYYLQTEPIPVLEVELDRP
GTLTTEFHFLP