Protein Info for UW163_RS19755 in Ralstonia solanacearum UW163

Annotation: DNA translocase FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 968 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 37 to 57 (21 residues), see Phobius details amino acids 77 to 103 (27 residues), see Phobius details PF13491: FtsK_4TM" amino acids 5 to 114 (110 residues), 27.8 bits, see alignment E=3.9e-10 PF17854: FtsK_alpha" amino acids 479 to 579 (101 residues), 90.9 bits, see alignment E=1.1e-29 PF01580: FtsK_SpoIIIE" amino acids 587 to 796 (210 residues), 257.1 bits, see alignment E=2.5e-80 PF09397: FtsK_gamma" amino acids 903 to 963 (61 residues), 89.9 bits, see alignment 1.4e-29

Best Hits

Swiss-Prot: 82% identical to FTSK1_RALSO: DNA translocase FtsK 1 (ftsK1) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03466, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family (inferred from 82% identity to rso:RS01655)

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (968 amino acids)

>UW163_RS19755 DNA translocase FtsK (Ralstonia solanacearum UW163)
MGLGWFGISSIWLLPLVWRYITRVMAGERGLKGPGTVRVWLATLAALCASASLEALTAGH
DAHGKAGGAAGRGLASLFTHMLGWSGAFLLMLGVLLWAAPMVFGRTWRQLLARLRKAGEA
APPEADAQQEDADNGLKPTALGLGGAEQAMLGGHAGAARPTGRQRGIESGAIWRQPAWQP
PPRTRESPPQPGEIWPLLNAQGLPEASSPAEAKPAAPAPAAPVKPAGDTPLLRPPLRAKI
VSSPFHHPRPSAGGQPSPSPAVDGVPSLPAEGEGLAMPAVAEADSPSNGAPDLAEPPTIP
VDLEAVRQEAEALLAELRDLMRPIAAAPSAPAVVLPKVEASPEAEASPEAEASPEVEVSP
EVEVSPEVEVSPEAEVLPEAVAALKAEAEAPAPETVAFAHPEGEAALGEAEAPALEPDHT
PVAAHEAVAPPLPAAPVQKPRIVLPAVVGQVVSNAMPAPAAVPVAVPPPAPPRVVDYRLP
NPELLTAASPDTASVSLEHLEDTGNLIAQRLAEFKVPVTVAGASAGPVITRFEVDPAIGV
RGAQVVGLMKDLARALGVTSIRVVETIPGKTCMGLELPNAQRAMIRLSEVVNAAEFQSHA
SHLVLAMGKDITGNPVVTDLARAPHLLVAGTTGSGKSVAVNAMILSMLYKATPEDVRLIM
IDPKMLELSVYEGIPHLLAPVVTDMKQAAHALNWCVGEMEKRYRLMSALGVRNLAGYNQK
IRVAQQAGHKVPNPFSLTPDVPEPLSTLPMIVVVIDELADLMMVAGKKIEELIARLAQKA
RAAGIHLILATQRPSVDVITGLIKANIPTRVAFQVSSKIDSRTILDQMGAETLLGQGDML
FLPPGTGYPQRVHGAFVADEEVHRVVEHWKQFGEPEYDEAILAGDPAEAAAGELFGEGGG
DAEADPLYDEAAAFVLNTRRASISAVQRQLRIGYNRAARLIEQMEAAGLVSPMGRNGSRE
VIAPGGSD