Protein Info for UW163_RS19310 in Ralstonia solanacearum UW163

Annotation: putative 2-aminoethylphosphonate ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 366 TIGR03265: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein" amino acids 15 to 366 (352 residues), 492.9 bits, see alignment E=2.9e-152 PF00005: ABC_tran" amino acids 32 to 174 (143 residues), 122.7 bits, see alignment E=3.6e-39 PF08402: TOBE_2" amino acids 291 to 332 (42 residues), 28.7 bits, see alignment 2.3e-10

Best Hits

KEGG orthology group: K02010, iron(III) transport system ATP-binding protein [EC: 3.6.3.30] (inferred from 84% identity to rpf:Rpic12D_4610)

Predicted SEED Role

"Ferric iron ABC transporter, ATP-binding protein" in subsystem Iron acquisition in Vibrio or Transport of Iron

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.30

Use Curated BLAST to search for 3.6.3.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (366 amino acids)

>UW163_RS19310 putative 2-aminoethylphosphonate ABC transporter ATP-binding protein (Ralstonia solanacearum UW163)
MLQTVSAPTPGVTSTFLSVRQVVRRFGAFTALDGVSLDVAQGEFVCLLGPSGCGKTTLLR
IIAGLEAQDAGRIVAGGRDISRLPPRERDYGIVFQSYALFPNLTVVQNVAYGLAAANGNR
ACMQARVAEMLALVGLAGSEAKYPAQLSGGQQQRVALARALAPAPSLLLLDEPMSALDAQ
VREHLRVELRRLQRRLNVTTLMVTHDQDEAMAMADRIAVMCDGRIEQTGTPAEIYTRPAT
GFVAGFVGQANWLPLQCADDGTPLLAGQPLLLDPAFADADALPAAGRLFCRPEAVTLNPD
ADAPNRHLARVVDRTYLGSRTRLTLALDGLADAPLVAEVASHALRGGLGEGKLWVALERD
GLRVYA