Protein Info for UW163_RS17710 in Ralstonia solanacearum UW163

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 411 transmembrane" amino acids 21 to 47 (27 residues), see Phobius details amino acids 59 to 81 (23 residues), see Phobius details amino acids 89 to 106 (18 residues), see Phobius details amino acids 111 to 129 (19 residues), see Phobius details amino acids 150 to 172 (23 residues), see Phobius details amino acids 178 to 199 (22 residues), see Phobius details amino acids 223 to 244 (22 residues), see Phobius details amino acids 265 to 284 (20 residues), see Phobius details amino acids 295 to 314 (20 residues), see Phobius details amino acids 320 to 340 (21 residues), see Phobius details amino acids 352 to 371 (20 residues), see Phobius details amino acids 383 to 402 (20 residues), see Phobius details PF07690: MFS_1" amino acids 28 to 366 (339 residues), 143 bits, see alignment E=5.6e-46 amino acids 236 to 408 (173 residues), 56.9 bits, see alignment E=8.8e-20

Best Hits

Swiss-Prot: 66% identical to FSR_ECOLI: Fosmidomycin resistance protein (fsr) from Escherichia coli (strain K12)

KEGG orthology group: K08223, MFS transporter, FSR family, fosmidomycin resistance protein (inferred from 93% identity to rso:RSp0412)

MetaCyc: 66% identical to fosmidomycin efflux pump (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-41

Predicted SEED Role

"Fosmidomycin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (411 amino acids)

>UW163_RS17710 MFS transporter (Ralstonia solanacearum UW163)
MDTTANGTAAAQARARAGTTGFGVIGAISFAHFLNDMMQSLILAIYPLLKGNFHLDFTQI
GLITLTYQITASLLQPMVGLYTDRHPKPYSLPVGMGFTLVGLLLLSMAPNFGTLLLAAAL
VGTGSSIFHPESSRVARMASGGRHGLAQSLFQVGGNVGSAMGPLLAAVVIMPYGQHSLAW
FSIAALIAMAVLVQVGGWYKRERAAGHGRKGEARASAAARLPAGKVAMAMLLLVVLLFSK
YFYLASLNSYYTFYLISKFHLSAQASQLFLFLFLFSVAVGTIAGGPIGDRFGRKVVIWVS
ILGVAPFTLLLPYANLFWTAVLTVIIGLVLASAFSAILVYAQELIPGKVGMVSGLFFGFA
FGLGGIGAAVLGKLADATDIHHVYHLCSFLPLIGLLTVFLPNIERPARQPA