Protein Info for UW163_RS15740 in Ralstonia solanacearum UW163

Annotation: L-lactate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 561 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 40 to 60 (21 residues), see Phobius details amino acids 68 to 89 (22 residues), see Phobius details amino acids 114 to 133 (20 residues), see Phobius details amino acids 139 to 160 (22 residues), see Phobius details amino acids 166 to 184 (19 residues), see Phobius details amino acids 196 to 214 (19 residues), see Phobius details amino acids 221 to 239 (19 residues), see Phobius details amino acids 245 to 265 (21 residues), see Phobius details amino acids 312 to 330 (19 residues), see Phobius details amino acids 368 to 393 (26 residues), see Phobius details amino acids 408 to 427 (20 residues), see Phobius details amino acids 437 to 460 (24 residues), see Phobius details amino acids 526 to 549 (24 residues), see Phobius details TIGR00795: transporter, lactate permease (LctP) family" amino acids 4 to 548 (545 residues), 507.5 bits, see alignment E=2.5e-156 PF02652: Lactate_perm" amino acids 15 to 546 (532 residues), 509.4 bits, see alignment E=6.2e-157

Best Hits

KEGG orthology group: K03303, lactate transporter, LctP family (inferred from 98% identity to rsc:RCFBP_20500)

Predicted SEED Role

"L-lactate permease" in subsystem Lactate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (561 amino acids)

>UW163_RS15740 L-lactate permease (Ralstonia solanacearum UW163)
MWNQVYDPLGNAVWSTIAAGLPVAVLLCSLAFFHMQAHLAAGLALIVGVSVAAFVFGMPT
AMAGKAAGLGIVSGLFPIGWIVLNIIFLHRLTTLNGSFKVLQSSISGITEDRRLQLLLVA
FSFGAFFEGAAGFGTPVAVTGAILIGLGFSPLAASGLALIANTAPVAYGALGAPVIGLAA
VTGLDLKDLSAMIGRQLPFFSVLVPFWLIWAFAGFRGMLQIWPAILVAGVTFAVPQFLVS
NFHGPWLVDVIGALISMGSLTLFLKVWKPKTIWTSTALRKHPDNSKVDPEAAAEARAATT
AGDVNISRVQAWLPWVILTVFVFIWGVPQFKAFVDGLWQFKFPIPGLDKMVLKGPPVVPK
VTAEGAVFTFNVLSMAGTGILASAVVGGLLMGYSVPRMVKEYWNTIKLTRYSLLTICAMF
GIGYLTRYSGLDATLGLAFAHTGVLYPLFGTMLGWLGVALTGSDTASNVLFGGLQKTTAE
QLGLSPILMSAANSSGGVMGKMIDAQSIVVASTATKWYGHEGDILRYVFFHSIALAFLVG
LMITLQAYVEPFTRLVVPMVR