Protein Info for UW163_RS15000 in Ralstonia solanacearum UW163

Annotation: oligopeptidase A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 706 PF19310: TOP_N" amino acids 39 to 159 (121 residues), 79.1 bits, see alignment E=2.5e-26 PF01432: Peptidase_M3" amino acids 235 to 696 (462 residues), 482 bits, see alignment E=2.8e-148

Best Hits

Swiss-Prot: 48% identical to OPDA_SALTY: Oligopeptidase A (prlC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01414, oligopeptidase A [EC: 3.4.24.70] (inferred from 98% identity to rsc:RCFBP_11602)

MetaCyc: 48% identical to oligopeptidase A (Escherichia coli K-12 substr. MG1655)
Oligopeptidase A. [EC: 3.4.24.70]

Predicted SEED Role

"Oligopeptidase A (EC 3.4.24.70)" in subsystem Protein degradation (EC 3.4.24.70)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.70

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (706 amino acids)

>UW163_RS15000 oligopeptidase A (Ralstonia solanacearum UW163)
MTVISPEVAPPAANPLLDFSGLPRFAEIRPEHITPALDTLLEHAAAAVARVKDPATPSTW
DRVVAALEDATEPLGRAWGIVSHLSAVADTPALREAHAANLPRVTEFWSGLGQDLELFKK
YKAIAESGEYATLTPARKKLLDNELRGFRLGGAELPEDRKPRFAAIQEQQAQLTKAFSDH
VLDATNGYALLIDDEARLSGLPEDARQAAHEAARRDNPHAAGWKFTLHFPSYFPVLQYAD
DRALRRTLYEANVTRASELGPQHGGGKPEWDNTANMAEQLALRAEEAHMLGYRNFGEVSL
VPKMADSPEEVLRFLGELADRARPFAEQDWTELQAFAKTTLGIDKLESWDMAYASEKLRE
ARYAFSEQEVKQYFPEPAVLDGLFDVVQTLFSVKIRPEPAEVWHPDVRFFRVESAQGELL
AQFYIDLYAREGKRGGAWMDDARGRKALAGAEVQTPVAYLTCNFSGPVGNKPALFTHDEV
ITLFHEFGHGLHHMLTQVDELGVSGINGVEWDAVELPSQFMENFCWEWEVLSRMTRHVES
GEPLPRALYERMLAAKNFQNGMATLRQIVFSTFDMHLHTDFDPKSATSVLALSRQINDRF
HVVPQAALSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAGKLSGSVLDAETG
ARYRREVLAVGGSRPAIESFTAFRGRAPTIDALLRHGGMVVTAEPV