Protein Info for UW163_RS14445 in Ralstonia solanacearum UW163

Annotation: amino acid transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 512 transmembrane" amino acids 23 to 43 (21 residues), see Phobius details amino acids 52 to 74 (23 residues), see Phobius details amino acids 104 to 126 (23 residues), see Phobius details amino acids 132 to 150 (19 residues), see Phobius details amino acids 160 to 183 (24 residues), see Phobius details amino acids 203 to 225 (23 residues), see Phobius details amino acids 246 to 267 (22 residues), see Phobius details amino acids 288 to 313 (26 residues), see Phobius details amino acids 348 to 366 (19 residues), see Phobius details amino acids 372 to 395 (24 residues), see Phobius details amino acids 417 to 436 (20 residues), see Phobius details amino acids 452 to 471 (20 residues), see Phobius details PF00324: AA_permease" amino acids 22 to 470 (449 residues), 478 bits, see alignment E=3.2e-147 PF13520: AA_permease_2" amino acids 23 to 442 (420 residues), 130.8 bits, see alignment E=6.9e-42

Best Hits

Swiss-Prot: 74% identical to LYSP_ECOLI: Lysine-specific permease (lysP) from Escherichia coli (strain K12)

KEGG orthology group: K03293, amino acid transporter, AAT family (inferred from 94% identity to rso:RSc1758)

MetaCyc: 74% identical to lysine:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-58

Predicted SEED Role

"Lysine-specific permease" in subsystem YeiH

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (512 amino acids)

>UW163_RS14445 amino acid transporter (Ralstonia solanacearum UW163)
MPEHTTASTATPGLRRTLRARHLTMIAIGGSIGTGLFVASGASVSQAGPGGALAAYVLIG
AMVYCLMTSLGELAAYMPVPGSFATYGARYVDEGFGFALGWNYWYNWAVTIAVELAAAQL
VMHYWFPDVPGVLWSAGFLAVMFLLNAISVRGFGEAEYWFALIKVVTVLCFIAIGLAMIF
GIIKGAPESGLHNLTIGDAPFVGGLPAMIGVAMIAGFSFQGTELIGVAAGESADPARTIP
RAVRQVFWRILLFYVLAIFIIGVLVPYTDPNLLSTDVANLGVSPFTLVFRHAGLAFAAGL
MNAVILTAVLSAGNSGMYASTRMLYNLATEGRAPRMFARLSKNGVPRNALLATTAVGALC
FLSSLYGDKTVYLWLLNTSGMTGFVAWLGIAISHYRFRKGLVLQGHDPAHLPYHSPFFPY
GPLFAFGLCLVITLGQNYQAFASGKIDWAEVTATYIGIPIFLAVWVGYRLVRGGGLIRYQ
DMHFPRPPVARDTPAGPLPDPGLPAAATSPQR