Protein Info for UW163_RS13700 in Ralstonia solanacearum UW163

Annotation: type I methionyl aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00500: methionine aminopeptidase, type I
  • amino acids 4 to 255 (252 residues), 309 bits, E=1.2e-96
• PF00557: Peptidase_M24
  • amino acids 13 to 248 (236 residues), 175.8 bits, E=5.3e-56

Best Hits

Swiss-Prot: 57% identical to MAP1_ECOL6: Methionine aminopeptidase (map) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K01265, methionyl aminopeptidase [EC: 3.4.11.18] (inferred from 100% identity to rsc:RCFBP_20030)

MetaCyc: 57% identical to methionine aminopeptidase (Escherichia coli K-12 substr. MG1655)
Methionyl aminopeptidase. [EC: 3.4.11.18]

Predicted SEED Role

"Methionine aminopeptidase (EC 3.4.11.18)" (EC 3.4.11.18)

MetaCyc Pathways

• Arg/N-end rule pathway (eukaryotic) (8/14 steps found)
• Ac/N-end rule pathway (6/21 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.18

Protein Sequence (275 amino acids)

>UW163_RS13700 type I methionyl aminopeptidase (Ralstonia solanacearum UW163)
MAVTLKTAEDIAHMRVACRLASEVLDYITPFVKAGVSTGELDRLCHAYMRDVQGTVPAPL
NYAPPGYPPFPGAICTSVNDVICHGIPDDKKILKNGDAVNLDITVITPEGYYGDTSRMFI
AGEGSILAKRLAQVTYECMWKGIAVVRPGARLGDIGHVIQQHAEAAGYSVVREYCGHGIG
KVFHEDPQILHYGRPGTGLELKAGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQW
EHTILVTETGYDVLTVSAHTPAPPEFVGDGTPATA