Protein Info for UW163_RS13650 in Ralstonia solanacearum UW163
Annotation: succinyldiaminopimelate transaminase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K14267, N-succinyldiaminopimelate aminotransferase [EC: 2.6.1.17] (inferred from 99% identity to rsc:RCFBP_20040)MetaCyc: 62% identical to N-succinyldiaminopimelate-aminotransferase (Bordetella pertussis)
Succinyldiaminopimelate transaminase. [EC: 2.6.1.17]
Predicted SEED Role
"N-succinyl-L,L-diaminopimelate aminotransferase alternative (EC 2.6.1.17)" in subsystem Lysine Biosynthesis DAP Pathway (EC 2.6.1.17)
MetaCyc Pathways
- aspartate superpathway (23/25 steps found)
- superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (16/18 steps found)
- L-lysine biosynthesis I (9/9 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.17
Use Curated BLAST to search for 2.6.1.17
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (403 amino acids)
>UW163_RS13650 succinyldiaminopimelate transaminase (Ralstonia solanacearum UW163) MPNTVNPRLSSLQPYPFEKLKALVKDVAPSPAHAPISFGIGEPKHPTPALVKDALTASLA GLANYPTTAGSDALRQCIAAWLERRYGLPKVDAATEVLPVNGSREALFAFAQTVIDGSKP GARVLCPNPFYQIYEGSALLAGAQPLFANSNPARNYAPDYDAITPEEWRNVQLVFVCSPG NPTGAVLTLDDWKRLFALSDEYGFVIASDECYSEIYFDEANPPLGALQAAHQLGRGFERL VMFSSLSKRSNVPGMRSGFVAGDAKLIKTYLLYRTYHGSAMNPAVQSASIAAWNDETHVR ENRAQYVKKFRSVTPMLAEVLDVALPDAAFYLWANVKRTGLSDTAFARELLAAKNVAVLP GSYLAREAHGVNPGQDYVRIALVASVDECLDGARRIVEFCQQR